Autoimmunity In Rheumatoid Arthritis Tempered By Regulatory Immune Cell Diversity

Untangling the root cause of rheumatoid arthritis has been a difficult task for immunologists, as decades of research has pointed to multiple culprits in our immune system, with contradictory lines of evidence…

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Arthritis – Anxiety Twice As Common As Depression

Approximately one third of adults with arthritis in the USA aged 45+ years suffer from anxiety or depression, researchers from the CDC reported in the journal Arthritis Care & Research. The authors added that the prevalence of anxiety in adults with arthritis is almost twice as high as depression, in spite of more studies focusing on the arthritis-depression link…

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Women At Greater Risk Of Knee Injuries

Women are more prone to knee injuries than men, and the findings of a new study suggest this may involve more than just differences in muscular and skeletal structure – it shows that males and females also differ in the way they transmit the nerve impulses that control muscle force…

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Discovery Of New Immune Defence Enzyme

Neutrophil granulocytes comprise important defences for the immune system. When pathogenic bacteria penetrate the body, they are the first on the scene to mobilise other immune cells via signal molecules, thereby containing the risk. To this end, they release serine proteases – enzymes that cut up other proteins to activate signal molecules…

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Osteoarthritis Pain Alleviated By Antidepressant

Antidepressants can play a key role in alleviating painful conditions like osteoarthritis and may result in fewer side effects than traditionally prescribed drug regimes, such as anti-inflammatories and opioids, according to a perspective paper published online ahead of print publication by the International Journal of Clinical Practice…

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Anti-NGF Testing – FDA Committee Says “Yes”

The development of Anti-NGF (anti-nerve growth factor) class of drugs should go ahead, the Arthritis Advisory Committee has told the FDA. The Committee is an advisory body that recommends what the FDA (Food and Drug Administration) should do. Although the FDA is not bound by the Committee’s recommendations, it nearly always tends to go along with their opinions…

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What Causes Leg Pain?

Leg pain refers to any kind of pain that occurs between the heels and the pelvis. There are many reasons for leg pain, and not all of them are caused by a problem that originates in the leg; some injuries or spinal problems can cause aches and pains in the leg(s). Leg pain can be long-term, transitory, intermittent, acute, or slowly progressive…

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Women With Rheumatoid Arthritis And Lupus Give Birth To Fewer Children

New research shows that more than half of women with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) have fewer children than desired…

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Early, Aggressive Treatment May Help Reduce Symptoms And Improve Joint Function In Psoriatic Arthritis (PsA)

Medications or biologic agents that target T-cells, white blood cells involved in the body’s immune system, appear to offer significant benefit to patients suffering from psoriatic arthritis (PsA), a type of arthritis that affects up to 48 percent of patients with the skin disease psoriasis, according to a new review article in the Journal of the American Academy of Orthopaedic Surgeons (JAAOS)…

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Annual Bleeding Events And Frequency Of Infusions Reduced By Preventive Hemophilia A Treatment

A Rush University Medical Center led international research team has announced that a treatment to prevent bleeding episodes in children with hemophilia A also is effective for adolescents and adults. The preventive therapy will “optimize care for hemophilia patients of all ages by stopping unexpected bleeding events that can have a detrimental impact on the lives of patients,” said Dr…

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