Psoriasis Linked To Increased Risk Of Cardiovascular Disease By Mechanistic Discovery

The link between psoriasis and cardiovascular events has been observed for years, however the mechanics were unknown. For the first time, Case Western Reserve University School of Medicine researchers have discovered preclinical evidence demonstrating that the inflammatory skin disease leads to cardiovascular disease…

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Brodalumab For Moderate To Severe Psoriasis Moving Into Phase III

Results from a Phase II, randomized, double-blind, placebo-controlled, dose-ranging trial designed to evaluate the efficacy and safety of brodalumab (formerly AMG 827) in 198 patients with moderate to severe plaque psoriasis have been published in the New England Journal of Medicine…

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A Link Between Atherosclerosis And Autoimmunity

Individuals who suffer from autoimmune diseases also display a tendency to develop atherosclerosis – the condition popularly known as hardening of the arteries. Clinical researchers at LMU, in collaboration with colleagues in Würzburg, have now discovered a mechanism which helps to explain the connection between the two types of disorder…

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Potential To Prevent Heart Attacks And Strokes By Treating Psoriasis

A clinical study co-led by the Montreal Heart Institute and Innovaderm Research Inc., which was presented at the annual meeting of the American Academy of Dermatology, shows that a new treatment for psoriasis could be associated with a significant decrease in vascular inflammation, a major risk factor of cardiovascular disease…

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No Protection Found Against Eczema With Prolonged Breastfeeding: International Study

The largest worldwide study on the association between breastfeeding, time of weaning and eczema in children has concluded that there is no clear evidence that exclusive breastfeeding for four months or longer protects against childhood eczema The largest worldwide study on the association between breastfeeding, time of weaning and eczema in children has concluded that there…

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Water Channels In The Body Help Cells Remain In Balance

Water channels exist not only in nature – microscopical water channels are also present in the cells of the body, where they ensure that water can be transported through the protective surface of the cell…

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Psoriatic Arthritis – Cimzia® (Certolizumab Pegol) Shows Promise

On Thursday, UCB announced its intention to submit regulatory applications for Cimzia® (certolizumab pegol) by the end of this year. The drug is designed to treat psoriatic arthritis, an inflammation of the joints, or arthritis, which typically occurs in combination with psoriasis, a skin disorder…

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Growing Up On A Farm Directly Affects Regulation Of The Immune System

Immunological diseases, such as eczema and asthma, are on the increase in westernised society and represent a major challenge for 21st century medicine. A new study has shown, for the first time, that growing up on a farm directly affects the regulation of the immune system and causes a reduction in the immunological responses to food proteins…

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All Itches Are Not Equal

New research from Gil Yosipovitch, M.D., Ph.D., professor of dermatology at Wake Forest Baptist Medical Center and a world-renowned itch expert, shows that how good scratching an itch feels is related to the itch’s location…

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Psoriatic Arthritis – New Drug Offers Relief

Around 7.5 million Americans, which is about 2.2% of the population, suffer from psoriaris, an autoimmune disease causing red, flaky skin…

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