Lithium For Bipolar Disorder – Pros And Cons Unclear

By roy, on January 29th, 2012%

The most effective long-term treatment for bipolar disorder is lithium. It offers protection against depression and mania and reduces the risk of suicide and short-term mortality. However, according to a study in The Lancet ,safety concerns have made the use of lithium controversial…

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Lithium Therapy Improvement By Reduction Of Its Toxicity

By roy, on July 29th, 2010%

Lithium is the most effective treatment for bipolar disorder. However, its use is limited because of neurological side effects and a risk for overdose-induced toxicity. Many of the beneficial effects of lithium are mediated by its inhibition of GSK-3 proteins, but whether this is the mechanism underlying its negative effects has not been determined…

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